MyBioSource.com's Rabbit Anti-Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, and ELISA. The Rabbit Anti-Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Antibody was generated using alkB homolog 3, alpha-ketoglutarate dependent dioxygenase, and ALKBH3 as the antigen and it reacts with Human.
Description
Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron